egg_allergy_comp

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Egg Component

A test for detection of allergic response to egg components.

  • Vibrant’s Egg Component test offers __% sensitivity and __% specificity to egg components, gives healthcare providers the most accurate picture of egg component allergic response available on the market. It eliminates the guesswork of skin prick tests and gives reliable answers clinicians can count on to make diagnostic decisions with certainty.
  • Allergy to ovomucoid proteins in egg indicates a sensitization to the protein component of egg that is heat stable and which will typically be a lifelong allergy.
  • Allergy to ovalbumin proteins in egg indicates a sensitization to the protein component of egg that is easily denatured in heat, and which some children outgrow as they age.
  • Patients with allergy to only ovalbumin proteins may be able to safely consume foods with cooked egg ingredients. Patients with allergy to ovomucoid proteins, regardless of whether they also have ovalbumin protein allergy, should not consume egg ingredients of any kind and will likely not outgrow their allergy to egg proteins.
EGG COMPONENT
ASSOCIATIONS
1) OVOMUCOID (GAL D 1)
More severe allergic response to egg; heat-stable protein
2) OVALBUMIN (GAL D 2 )
Easily denatured by heat, which means some with this sensitization may be able to consume foods with cooked egg ingredients; allergic response may be outgrown in some individuals

Symptoms and Risk Factors Associated with Egg Allergy Include:

  • Asthma
  • Coughing, wheezing, or shortness of breath
  • Eczema and other rashes
  • Hives
  • Runny nose/nasal congestion
  • GI symptoms: nausea, vomiting, cramping
  • Anaphylaxis
  • Because the Vibrant Egg Component test uses a small amount of blood from the patient, there is no need to expose a high risk patient to a food that may cause allergy, through skin prick or food challenges.
  • The Vibrant Egg Component can aid healthcare providers in differentiating egg allergies that can be managed by total avoidance of all egg ingredients or whether a patient can safely consume some products with cooked egg ingredients.
  • Patients with allergy to only ovalbumin proteins may be able to safely consume foods with cooked egg ingredients. Patients with allergy to ovomucoid proteins, regardless of whether they also have ovalbumin protein allergy, should not consume egg ingredients of any kind and will likely not outgrow their allergy to egg proteins.
  • Consider running a concurrent Vibrant Egg Zoomer with Egg Component in order to test the full spectrum of reactivity to eggs – from mild sensitivity to severe high risk anaphylaxis. The Vibrant Egg Component test covers all IgE reactions to eggs, while the Vibrant Egg Zoomer covers IgG and IgA reactions, which are less severe, but can still produce uncomfortable symptoms in sensitive patients.

What is the difference between the Egg Component test and the Egg Zoomer?

The Vibrant Egg Component test is a screen for allergic reactions or allergic sensitization to egg peptides and components, which involve IgE antibodies to the measured peptides.

The Vibrant Egg Zoomer is a test for sensitivity to egg peptides, which involve IgG and IgA antibodies, and which are not allergic sensitivities.

We recommend running both tests in order to detect the most possible reactions to eggs in all immunoglobulin (Ig) arms of the immune system.

My Egg Component test shows positive antibodies to egg, but I do not experience any symptoms when I consume eggs. Is my test wrong?

Many patients have been sensitized to eggs, which means an initial exposure has triggered the production of IgE (allergy specific) antibodies to this food. These antibodies can be detected in the blood of sensitized individuals. However, because of many variables, antibodies do not always correlate with symptoms and not all egg component peptides are associated with anaphylaxis or severe, life-threatening allergies. Because of this, you may have elevated antibodies on the Egg Component Allergy panel, but may not be highly allergic yet. Your healthcare provider will aid you in interpretation of results in conjunction with your symptoms and medical history.

Can I run the Egg Component test in pediatrics?

Yes. While Vibrant has not created reference ranges specific to pediatric populations, this test can and should be run in pediatric populations that are at risk for or suspected of having egg allergies or sensitization.

Recommended Tests to Consider 

menu_egg
Egg Zoomer
egg_allergy_comp
Peanut Component
menu_wheat
Wheat Zoomer

The general wellness test intended uses relate to sustaining or offering general improvement to functions associated with a general state of health while making reference to diseases or conditions. This test has been laboratory developed and its performance characteristics determined by Vibrant America LLC, a CLIA-certified laboratory performing the test. The test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests.